Chamber: The device along with the MDI plastic elbow should be washed at least once a week using warm water and a liquid dishwashing detergent. Place the whole unit in warm water before trying to remove flexible MDI end. Then wash the unit, rinse with warm clear water and allow to air dry. Mask: Oils from the skin can, over time, reduce the flexibility of the silicone. It is recommended that the mask be cleaned after each use. To clean, hand wash with a mild detergent and warm water. Rinse well and allow to air dry. Inspect the mask, including the one-way valve, after every cleaning.